Scientists have cured mice of Type 1 with gene therapy. Apparently it will work for Type 2 as well, though a lot of that is caused by following terrible nutrition advice.
Category Archives: Health
ObamaCare
“My husband would have died if he’d relied on it.”
All of the mendacious hysteria over this bill has been incandescent, especially compared to the very real disaster that the ACA has been (and which many of us warned about).
Who would've guessed the same folks who said Mitt gave a lady cancer & plans to kill Big Bird would exaggerate about GOP legislation.
— Razor (@hale_razor) May 6, 2017
Who would've guessed the same folks who said Mitt gave a lady cancer & plans to kill Big Bird would exaggerate about GOP legislation.
— Razor (@hale_razor) May 6, 2017
Dems telling even more lies to prevent this bill than they did to pass Obamacare. Impressive, in a way. Wouldn't have thought it possible. https://t.co/qkzzPcYw8c
— Rand Simberg (@Rand_Simberg) May 6, 2017
Calorie Counting
It’s junk science, and these menu rules based on it are insane, and probably impossible to follow.
In related news, studies showing the dangers of replacing saturated fat with vegetable oils were apparently buried for a long time.
An Artificial Kidney
Available within two years? If so, this will save a lot of lives, and perhaps end the need for waiting for donors (which, unlike other organs, could be solved by simply letting the market work).
Candy And Soda
Most Americans don’t think they should be able to be purchased with food stamps.
I agree. I oppose food stamps (it’s a federal subsidy to farmers), but if you’re going to give them out, they should only be used for food.
Calico’s Anti-Aging Research
What is it doing?
Mindless Eating
Problems with p-hacking are by no means exclusive to Wansink. Many scientists receive only cursory training in statistics, and even that training is sometimes dubious. This is disconcerting, because statistics provide the backbone of pretty much any research looking at humans, as well as a lot of research that doesn’t. If a researcher is trying to tell whether changing something (like the story someone reads in a psychology experiment, or the drug someone takes in a pharmaceutical trial) causes different outcomes, they need statistics. If they want to detect a difference between groups, they need statistics. And if they want to tease out whether one thing could cause another, they need statistics.
The replication crisis in psychology has been drawing attention to this and other problems in the field. But problems with statistics extends far beyond just psychology, and the conversation about open science hasn’t reached everyone yet. Nicholas Brown, one of the researchers scrutinizing Wansink’s research output, told Ars that “people who work in fields that are kind of on the periphery of social psychology, like sports psychology, business studies, consumer psychology… have told me that most of their colleagues aren’t even aware there’s a problem yet.”
I think the hockey stick episode shows that this is a problem with climate research as well.
The point of peer review has always been for fellow scientists to judge whether a paper is of reasonable quality; reviewers aren’t expected to perform an independent analysis of the data.
“Historically, we have not asked peer reviewers to check the statistics,” Brown says. “Perhaps if they were [expected to], they’d be asking for the data set more often.” In fact, without open data—something that’s historically been hit-or-miss—it would be impossible for peer reviewers to validate any numbers.
Peer review is often taken to be a seal of approval on research, but it’s actually more like a small or large quality boost, depending on the reviewers and scientific journal in question. “In general, it still has a good influence on the quality of the literature,” van der Zee said to Ars. But “it’s a wildly human process, and it is extremely capricious,” Heathers points out.
There’s also the question of what’s actually feasible for people. Peer review is unpaid work, Kirschner emphasizes, usually done by researchers on top of their existing heavy workloads, often outside of work hours. That often makes devoting the time and effort needed to catch dodgy statistics impossible. But Heathers and van der Zee both point to a possible generational difference: with better tools and a new wave of scientists who aren’t being asked to change long-held habits, better peer reviews could conceivably start to emerge. Although if change is going to happen, it’s going to be slow; as Heathers points out, “academia can be glacial.”
“Peer review” is worse than useless at this point, I think. And it’s often wielded as a cudgel against dissidents of the climate religion.
“Settled Science”
How it helped create a massive public-health disaster.
You can guess what this one is about. It killed my father. I wish I could tell it to prepare to die, but it may finally be happening, anyway.
[Update a while later]
Ron Bailey reviews a new book on an epidemic of epidemiology.
Choice In Health Care
Trump starts to give it to veterans.
But wait! I thought single-payer was great?
AI In Medicine
Self-taught systems beat MDs at predicting heart attacks:
All four AI methods performed significantly better than the ACC/AHA guidelines. Using a statistic called AUC (in which a score of 1.0 signifies 100% accuracy), the ACC/AHA guidelines hit 0.728. The four new methods ranged from 0.745 to 0.764, Weng’s team reports this month in PLOS ONE. The best one—neural networks—correctly predicted 7.6% more events than the ACC/AHA method, and it raised 1.6% fewer false alarms. In the test sample of about 83,000 records, that amounts to 355 additional patients whose lives could have been saved. That’s because prediction often leads to prevention, Weng says, through cholesterol-lowering medication or changes in diet.
To be honest, while it’s statistically significant, I’d have expected a bigger improvement than that. And it’s not clear how useful it is if the recommendations aren’t science based, as prescribing cholesterol-reduction or diet change generally aren’t.