It’s complicated. Chemo also is used in laboratory conditions to *induce* senescence in cells…and amelioration of chemotherapeutic damage is one of the indications for senolytic therapy.
More: http://www.oisinbio.com (specifically see the PDF link under the “News” blurb for the International Cell Senescence Association meeting in Montreal in July of this year.
Have you seen David Sinclair’s recent video?
He’s working on a theory that ageing is primarily due to cells forgetting what kind of cell they are, because the wrong genes are expressed in the cell due to a failure of the DNA repair system. So it may turn out that senescent cells are just a consequence of that.
Okay, good, now how do we get rid of them?
Pretty much a single dose of chemotherapy:
https://www.nih.gov/news-events/news-releases/senolytic-drugs-reverse-damage-caused-senescent-cells-mice
It’s complicated. Chemo also is used in laboratory conditions to *induce* senescence in cells…and amelioration of chemotherapeutic damage is one of the indications for senolytic therapy.
More: http://www.oisinbio.com (specifically see the PDF link under the “News” blurb for the International Cell Senescence Association meeting in Montreal in July of this year.
Have you seen David Sinclair’s recent video?
He’s working on a theory that ageing is primarily due to cells forgetting what kind of cell they are, because the wrong genes are expressed in the cell due to a failure of the DNA repair system. So it may turn out that senescent cells are just a consequence of that.
https://www.youtube.com/watch?v=DofU0GRtM9w
All that said, I’ll certainly consider getting a senescent cell clearout therapy when it’s available.