One of the prevailing myths of modern life (I use the word here in the sense of something that everyone believes, not necessarily something that is false) is that cholesterol causes heart disease and stroke, and that reducing it will reduce the risk of heart disease and stroke. But the recent Vytorin issue should give us cause to question this conventional wisdom.

Whenever I’ve looked at the research, I’ve never been able to see any clear indication that taking cholesterol-reducing medication actually reduces risk, per se–all that the clinical studies that I’ve seen seem to indicate is that cholesterol reduction is taking place. But correlation is not causation. It could be that both high cholesterol and vascular disease are caused by some third factor that hasn’t been identified, and that in reducing cholesterol, whether by diet or medication, or both, we are treating a symptom rather than a cause.

My point is, that I don’t know the answer. But I don’t have a lot of confidence that the medical community does, either. And I remain wary of taking medications with unknown side effects and potential for interaction with other things I ingest, when the benefit is unclear. And I write this as someone who lost both parents to heart disease (my father’s first heart attack occurred when he was about forty five, and he died from a second one about a decade later). But they also had much different lifestyles than I did–they grew up with poor diets during the depression, they both smoked like chimneys, and they were both overweight. So I don’t necessarily believe that genetics is destiny, at least in this case.