“We found that the offspring of nonagenarians who had at least 1 nonagenarian sibling had lower levels of vitamin D than controls, independent of possible confounding factors and SNPs [single nucleotide polymorphisms] associated with vitamin D levels,” write the authors. “We also found that the offspring had a lower frequency of common genetic variants in the CYP2R1 gene; a common genetic variant of this gene predisposes people to high vitamin D levels.
These findings support an association between low vitamin D levels and familial longevity.” They postulate that offspring of nonagenarians might have more of a protein that is hypothesized to be an “aging suppressor” protein. More research is needed to understand the link between lower vitamin D levels, genetic variants and familial longevity.
Of course, correlation is not causation. For now, I think I’ll continue to supplement.
For what it’s worth, my dad died at fifty-five, a third of a century ago, in large part due to criminal dietary advice (OK, maybe that’s a little too strong — they probably knew no better) and my mother at sixty-eight to a massive heart attack in the night, in her sleep. At least for her, it was fast. And in both cases they were overweight smokers, a product of their generation.
Here’s an intersection of two of my favorite topics — the heavy hand of the state in regulating speech, and paleolithic diets, from George Will. And good for the Institute for Justice.