This mouse study seems very promising, but there is a word missing here:
In consideration of the challenges and side effects associated with prolonged fasting in humans, we developed a low-calorie, low-protein and low-carbohydrate but high-fat 4-day fasting mimicking diet (FMD) that causes changes in the levels of specific growth factors, glucose, and ketone bodies similar to those caused by water-only fasting (Brandhorst et al., 2015) (see also Figure S1 for metabolic cage studies). Here, we examine whether cycles of the FMD are able to promote the generation of insulin-producing β cells and investigate the mechanisms responsible for these effects.
It’s called “ketogenic,” people. Kee Toe Jen Ick. Low carb, high fat.
…wonders why NASA is considering crewing the first flight of SLS/Orion:
In a statement at the beginning of the Feb. 23 meeting of the Aerospace Safety Advisory Panel (ASAP), chairwoman Patricia Sanders said that if NASA decides to put a crew on the first SLS/Orion launch, Exploration Mission 1 (EM-1), it must demonstrate that there is a good reason to accept the higher risks associated with doing so.
“We strongly advise that NASA carefully and cautiously weigh the value proposition for flying crew on EM-1,” she said. “NASA should provide a compelling rationale in terms of benefits gained for accepting additional risk, and fully and transparently acknowledge the tradeoffs being made before deviating from the approach for certifying the Orion/SLS vehicle for manned spaceflight.”
“If the benefits warrant the assumption of additional risk,” she added, “we expect NASA to clearly and openly articulate their decision-making process and rationale.”
The point of my book was not that NASA should simply be more accepting of risk, or be reckless, but balance the risk against the reward. In my opinion, accelerating commercial crew would be worth the risk, to end our dependence on Russia, and increase the productivity of the ISS. Redoing Apollo 8 half a century after the original as a political stunt would not.
It was the Bills Gerstenmaier and Hill. Gerst is always deadpan, but one had the impression that he’s not enthusiastic. They’re doing a feasibility study because the White House asked, and won’t be making any recommendations, just describing would it would take in terms of changes in schedule and budget. They just want to see “if they can fly crew sooner.” They expect to have some answers in a month or so (presumably as part of the input for FY2018 budget request). I wish the White House would ask them if they could fly crew sooner on Dragon and Starliner. That would be worth doing.
I can’t believe I just typed the words “FY 2018 budget request.” Makes me feel old.
I’d note that the reason they would only have two crew is probably a) to reduce the number of losses if it doesn’t go well and b) more margin in the (primitive?) life support.
[Saturday-afternoon update]
Amy Shira Teitel (like me) thinks that this makes no sense.
…is trying to decode death. Though, in reading, it’s more complicated than the headline. I heard him speak at a space conference a few years ago, interesting guy. And I’m fascinated by the hostility from his fellow scientists.
At least the community is starting to wake up to the hazards of sugar. I’ve seen a proposal to make food stamps ineligible for items containing it. Makes sense to me. It could help a lot with the obesity epidemic.
Considering the above, no one in their right mind would take any kind of dietary advice provided by the authorities at face value. It’s little wonder then that so many are taking matters into their own hands. Thirty years ago, if the USDA, AHA, or AMA told you something was bad for you, you stopped eating it. You didn’t question, because they were the ones with credibility and years of study. It was simply too much trouble for the average person to find the information they needed. Thankfully with the internet, all of the information needed is now available to anyone who wants it. We no longer have to put blind trust in authority figures because we can sift through the information ourselves and ask the right questions. If anything, the glut of information shows that the public’s trust in nutrition advice given by the authorities and media was sorely misplaced.
Same thing with climate, for the same reasons: there’s a lot of public policy, and money, at stake.
Of course, it’s worth noting that cryonicists do believe that patients in suspension aren’t dead. That only occurs after information death (as occurs rotting in a grave, or being cremated).
Professor Curry said: “It’s not just the fact that climate simulations are tuned that is problematic. It may well be that it is impossible to make long-term predictions about the climate – it’s a chaotic system after all. If that’s the case, then we are probably trying to redesign the global economy for nothing”.
I’ve been saying that’s likely the case for years. I’ll look forward to reading her paper.
Working on a new venture, an op-ed about the hypocrisy of the NASA safety culture, renovating the house, and a long essay on the potential for private robotic planetary exploration.