Is real longevity treatment just around the corner?
People blessed with anti-ageing genes tend not to get seriously ill but die suddenly at the end of their lives, Prof Barzilai pointed out.
‘I’m seeing 100-year-olds who are not only 100 years old but in great shape,’ he said.
‘They’re driving and painting, and they say life is beautiful.
‘I have this bias that makes me believe we have the ability as a species to get to 100 if we prevent some of these age-related diseases.
‘The cost of treating 100-year-olds in their last two years of life is a third of what it costs to treat somebody aged 70 to 80. At the end of their life they die, basically, all of a sudden.
‘People who die between 70 and 80 are sick in the last few years of their life. Centenarians are dying healthy.’
Studies had revealed a strong association between reaching 100 years of age and very high blood levels of HDL, which appear to run in families, said Prof Barzilai.
Not only were HDL levels important, but also the size of the cholesterol particles. Centenarians with this HDL profile were powerfully protected against Alzheimer’s, one of the greatest causes of disability and death in old age. A similar effect was being sought by the drug companies targeting CETP.
Prof Barzilai described his “vision” as a once-daily pill which staved off the effects of old age and would probably be taken when a person reached their 40s or 50s.
Works for me. I hope, anyway.