Young Blood

…the fountain of youth?

Tissue from the hippocampus of old mice given young blood showed changes in the expression of 200 to 300 genes, particularly in those involved in synaptic plasticity, which underpins learning and memory. They also found changes in some proteins involved in nerve growth.

The infusion of young blood also boosted the number and strength of neuronal connections in an area of the brain where new cells do not grow. This didn’t happen when old mice received old blood.

To find out whether these changes improved cognition, the team gave 12 old mice eight intravenous shots of blood plasma either from a young or an old mouse, over the course of one month. They used plasma rather than whole blood to exclude any effect produced by blood cells.

The mice then took part in a standard memory task to locate a hidden platform in water. The old mice that had received young blood plasma remembered where to find the platform much quicker than the mice on the old plasma.

Of course, this is the theme of many a science fiction story in which a rich evil codger kidnaps youth to drain their blood and preserve his own vitality. But I hope it turns out to be right, and they can figure out how to extract and manufacture whatever it is.

Fog Of War?

…or fog of lies?

Col. David Hunt has persuaded me that the attack was followed in real time not merely by the State Department but more than a hundred people in the White House situation room as well as in similar facilities within DoD and intelligence agencies. Logs [would have been] kept noting what officials entered these facilities, when they were notified, what decisions were requested/made, what was said by officials, etc., etc.

Col. Hunt paints this picture based not on direct knowledge but on his extensive knowledge of how these government agencies conduct crisis management operations. Obviously, in a six hour crisis there was plenty of time for all the various crisis management facilities to come on line, something that Col. Hunt depicts as happening pretty much instantly.

I am persuaded by this picture, and I think it leaves a dramatic — and much more damning — impression of the alleged confusion, passivity, and disengagement of the president.

Sounds about right.

Biting Commentary about Infinity…and Beyond!