Finding The Cure

This is a pretty cool distributed computing project

Proteins are biology’s workhorses — its “nanomachines.” Before proteins can carry out these important functions, they assemble themselves, or “fold.” The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery.

Moreover, when proteins do not fold correctly (i.e. “misfold”), there can be serious consequences, including many well known diseases, such as Alzheimer’s, Mad Cow (BSE), CJD, ALS, Huntington’s, Parkinson’s disease, and many Cancers and cancer-related syndromes.

You can help by simply running a piece of software.

Folding@home is a distributed computing project — people from throughout the world download and run software to band together to make one of the largest supercomputers in the world. Every computer takes the project closer to our goals. Folding@home uses novel computational methods coupled to distributed computing, to simulate problems millions of times more challenging than previously achieved.

I thought that SETI@home was an interesting application, but this seems a lot more useful to me. I may set it up to run on my file server, which has a 64-bit AMD CPU that’s idle much of the time. It will help justify the electricity costs to run it.

Something To Be Thankful For

Life is such a bowl of cherries, and devoid of actual news (news here being defined in the traditional media sense of mayhem and misery), that here in south Florida, at least, the local teevee station is going to have team coverage of people lined up for the capitalist bacchanalia that commenced in the wee hours of the morning at the malls.

Now that’s news I can’t use. But I’m glad to hear there’s nothing of importance to cover.

Oh, and speaking of the local news team, the Weather Weasel* (my nickname for Chris Farrell, the perky little guy in the Princeton haircut who serves up the lack of weather here every morning on Channel 29 out of West Palm) lied to me again. All week, he and the other meteorological prognosticators have been threatening a Front (not a cold front–those hardly ever happen down here–even when they call them that, they’re just a Slightly Less Warm Front) would be coming through on Turkey Day, bringing Increased Clouds (words apparently meant to instill fear in the tremulous heart of a Sunshine Stater), and perhaps even the dreaded Isolated or (worse yet) Scattered Showers. Maybe, just maybe, even a Thundershower. Things would be even more dire on Friday, supposedly. Bear in mind that all these “warnings” come in the midst of a continuing drought as we head steadfastly into dry season, the dud of what was supposed to be an above-average hurricane season, from which we barely got one tropical storm on the first day of the season, ending one week from today. While Lake Okeechobee is five feet below normal.

Now what most people around here consider a threat, I consider a promise–a sacred one. Anyway, here it is, Friday morning. The dreaded Front stalled up around Orlando, and the sky is cloudless.

OK, you’re saying, weathermen aren’t perfect. They misjudged how far it would make it before the stalling process.

Fair enough. But here’s what really bugs me. If they’d admit that they were wrong, and explain what happened, and how they’re going to adjust the models so they’ll get it right next time, I’d be fine with it. But no. It’s Orwellian. On the forecast this morning, he made absolutely mention of the previous warnings, the most recent of which was last night, at 11:15 PM, just before I hit the pillow.

Just said, hey, it’s a sunny day, gonna be beautiful, just like it’s supposed to be down here. Maybe even warmer than normal. As though he and the others had not promised (well, at least to me) us all the Horrid Weather to come all week. Just down the memory hole, as though it never happened.

I dunno, maybe it’s just me. I hear stories of people who live up in the Pacific Northwest, who get depressed at what seems to be incessant clouds and drizzle and general dreariness, and take great joy when the sun pokes its head through the holes. Well, give me Seattle. I get despondent at the thought of this ongoing unremitting solar bath. I look forward to clouds, and rain, particularly if accompanied by thunder and lightning, but now that we’re heading into what passes down here for winter, I’m just in for one long soul-sucking period of non-weather for the next several months, which is simply made all the worse by the weathercasters’ continual glee in telling me that it will continue, while occasionally teasing me with the possibility of a change (with somber demeanor), only to shatter my dreams and then pretend they never did it.

Oh, well. At least the heat and humidity are down.

*I’m sure he’s a very nice fellow, and perhaps Weather Chipmunk would be a more appropriate nickname, but it doesn’t have the alliterative quality of the “W” word. And he does dash my hopes so often.

Forty-Four Years

This Thanksgiving is also the forty-fourth anniversary of the Kennedy assassination.

When we were in Dallas for a wedding a couple weeks ago, we went over to Dealey Plaza, where we’d never been, and went to the Sixth Floor Museum. I’d watched the coverage at the time it happened, and seen many photos and the Zapruder film, but you can’t really get a sense of what it is like without actually seeing the historic site of the assassination. It wasn’t what I’d imagined. I think that I’d always inflated the distances in my mind. It seemed almost mundane to look at the street that the limo had driven down, and up at the window of the repository where the sniper had lurked in wait.

Anyway, here’s an interesting article about the Zapruder film, and the mythology about it, that helps explain something that has provided fodder for the conspiracy theorists over the years.

Idiot Television Writers

I’m watching “Back To You,” a new sitcom with Kelsey Grammar and Patricia Heaton, while getting ready to brine the turkey for tomorrow.

He is overfeeding the goldfish, and she warns him not to do this (it’s a metaphor about what a lousy absentee dad he is, to put it in context of the ongoing plot).

The goldfish, of course, because this is television, dies immediately from overeating.

The only problem is that no goldfish ever died from overeating. Or at least, that’s not why you shouldn’t overfeed a goldfish (nor is the related Dr. Seuss story worth worrying about either).

It’s bad to overfeed fish because they won’t eat all the food, and the uneaten food will rot and pollute their bowl. It happens over a period of many hours or days, not instantaneously. But the dumb writers think that the fish gorge themselves and die (otherwise, they’d have no story line).

Arbiters Of Morality?

Jonah Goldberg writes:

It is, for example, absurd that we’ve decided the Supreme Court should be the final arbiter of morality in this country and it is even more cockeyed that, having arrived at this absurd place, we continue to appoint lawyers to the court on the assumption they are the experts best qualified to adjudicate not merely the law (which is fine, of course) but right and wrong and all of the mysteries of metaphysics and meaning. Why lawyers? Why not priests, doctors and philosophers too

Obama’s Space “Policy”

Well, we now have a second space policy statement from a Democrat candidate for president, this from Barack Obama, with further elaboration here.

As Jeff Foust notes, it doesn’t seem to be very well thought out, and he may indeed not recognize just how radical a proposal it is.

I certainly don’t support it, not because I would be broken hearted at a “delay” (which might effectively become a cancellation, once it becomes clear a few years down the road that private alternatives are going to beat it to orbit) of Constellation at this point, given what a pigs breakfast it seems to have become in the form of ESAS, but rather because I see little (and in fact negative) value in pouring another ten billion dollars into the rathole called federal education spending.

From a political standpoint, I don’t think that it would affect his electoral prospects, other than in the swing state of Florida (and perhaps Ohio, with Glenn). As others comment there, I do find it a little disappointing that the Senator views NASA simply as cash source for social spending. NASA’s money is not well spent, but I’d rather see a policy debate on how it could be spent to get better results in terms of NASA’s charter, than whether or not they should have it. But such a debate (and associated analysis) is surely far beyond whoever is advising Obama on such things.

There’s a lot of discussion in comments, and I agree with “anonymous” that had NASA stuck with the original Steidle plan, and had the CEV flyoff by now, the program would be a lot harder to kill in 2009. As it is, given all the technical issues and delays it’s facing, and potential loss of momentum, the program is in danger of cancellation almost regardless of who the next president is.

[Update a couple minutes later]

Clark Lindsey has similar thoughts:

I would prefer that a President Obama offer a smarter manned program rather a minimized manned program.

Don’t hold your breath on that, though, from Obama (or really, any other candidate, including the Republican ones, unless by some miracle Gingrich were to get into the race).

Also Democrat Ferris Valyn has further thoughts.

Biting Commentary about Infinity…and Beyond!