I’ve been mulling the idea of keeping my lab notes on my Mac for a while, and I’ve started moving in that direction. The problem with keeping notes on a computer rather than on paper is that the computer is far less flexible. It’s much more powerful, but it’s quite constrained by the need for exactly the right software. The major advantage of a computer over a lab notebook is that you can put in a whole lot more data, and interlink the data in ways that you just can’t with paper.
The ideal lab notebook software would combine some of the functionality of a blog with some of the functionality of a wiki. The blog function would be to simply keep a log of all entries, with timestamps. The entries would consist of text, images, and tables of data. The wiki function would integrate the linear collection of entries from the blog to build up a coherent time-independent picture of the object under study. The wiki would include both information about the current state of the experiment and a set of tentative conclusions about the phenomenon under study, along with things like lists of references with comments.