Category Archives: Economics

A New Antibiotic Weapon Against Superbugs

This development looks promising. and this is the best part:

SNAPPs appear to pose no threat to healthy tissue, they only attack bacteria. This is in marked contrast to antibiotics that are known to have unpleasant side-effects under certain conditions because they damage both bacteria and healthy tissue. Why do the SNAPPs leave healthy tissue alone? Because the SNAPPs are too big to interact effectively with mammalian cell tissue. They’re like big dogs that attack other big dogs to establish dominance while ignoring tiny dogs that are beneath their notice.

SNAPPs appear to have the potential to work as a substitute in cases where AMR makes treatment with antibiotics ineffective. This is a very good thing, but is it also another short-term solution? Will the bacteria mutate and develop resistance to SNAPPs the same way they have developed resistance to antibiotics?

Lam and her team examined this question by exposing 600 generations of a colistin-resistant superbug to SNAPPs. The superbug the researchers used is known to mutate and acquire antibiotic resistance rapidly but the SNAPPs killed the 600th generation as effectively and easily as they did the first. The researchers speculate that the bacteria are unable to develop resistance because there are so many ways the SNAPPs can kill them.

Faster, please.

The Space Launch System

A history. I’d dispute this, though:

“Humans are pretty needy,” Lyles told me. “You’re taking water, you’re taking all of their environmental control systems, and whatever they need on a really long mission. A large, heavy launch vehicle is almost a no-brainer.”

NASA is not alone in this conclusion. During a two-week span last month, private companies SpaceX and Blue Origin both unveiled giant, SLS-scale launchers that will become key parts of their future spaceflight aspirations.

One of these things is not like the others. SpaceX and Blue Origin want to build big rockets because they plan to put thousands of people into space. NASA is doing it because Congress wants to keep thousands employed in the right zip codes (as the article makes clear).

SpaceX’s Announcement

A preview:

[Update a while later]

Here’s Nadia Drake’s story on the announcement. The Q and A ended up being sort of a goat rodeo.

[Update early evening, PDT]

Here’s the full presentation.

[Wednesday-morning update]

Here’s Eric Berger’s take, and Jeff Foust’s. And one from Casey Dreier at the Planetary Society.

[Update a couple minutes later]

And Chris Davenport’s.

[Update a couple more minutes later]

And Loren Grush says there’s still a lot to figure out. No kidding.

[Update another couple minutes later]

And Wayne McCandless is skeptical (with a plug of my book).

[Update a few minutes later]

Thoughts from Bob Zubrin.

[Update a while later]

Joel Achenbach says don’t pack your bags for Mars yet. And Ken Chang says Elon just needs to figure out how to pay for it. Well, I think there are other issues as well. Meanwhile, the National Space Society is gung ho (as they should be, it’s much more in line with the group’s stated objective than anything NASA is doing).

[Update a couple minutes later]

Miri Kramer’s five takeaways.

[Update late morning]

McCandless link was missing, but I fixed it.

In response to Dreier:

[Update early afternoon]

Here’s Alan Boyle’s take.

And Elon answered yesterday’s question about how they get down to the surface:

[Update a while later]

Bill Nye doesn’t buy it. But the Planetary Society doesn’t want “filthy meatbag bodies” on Mars, anyway.

Speaking of which, I’m pretty sure that this announcement will re-energize the SJWs.

[Update a while later]

An amusing take over at Wait But Why. And one of the first, but certainly not last takes on planetary protection and the Outer Space Treaty.