Category Archives: Technology and Society

History, Political Commentary, Technology and Society

The Long View

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Putting current events into perspective:

Long after the time in which anyone can easily recall who was US president in 2011, or what party was in power, or which wars of declining empire were fought, and then long after anyone even cares about that ancient history, and later, long after the whole downward slope of the history of the US is but a footnote of interest to scholars of the transition from second to third millennium, and later still, long after anyone can even find out with any great reliability who was US president in 2011 … long after all these things are forgotten, the first half of the 21st century will still be clearly recalled as the dawn of the era in which aging was conquered.

It will also be remembered as the era in which we finally opened up the rest of the solar system to human endeavors after the false start of the mid-twentieth century.

Business, Space, Technology and Society

Jeff Bezos

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An interesting interview. It’s mostly about Amazon’s business model and plans, but Blue Origin does come up:

Levy: You have a separate company called Blue Origin that hopes to send customers into outer space. Why is that important to you?

Bezos: It is a serious effort. When I was 5 years old, I watched Neil Armstrong step onto the moon. It made me passionate about science, physics, math, exploration.

Levy: Will you walk on the moon someday?

Bezos: Me? Are you saying would I if I could?

Levy: I bet you’d like to, but do you think you will?

Bezos: Boy. I’ve been asked to make tough predictions before. That one’s very tough. But that’s not what this is about. If I wanted to buy tourist trips to fly to the International Space Station and Soyuz and those things, there’s nothing wrong with that. But that’s $35 million. I want to lower the cost of access to space.

Levy: How do you do that?

Bezos: I like to say, “Maintain a firm grasp of the obvious at all times.” For Amazon, that’s selection, speed of delivery, lower prices. Well, for Blue Origin it’s cost and safety. If you really want to make it so that anybody can go into space, you have to increase the safety and decrease the cost. That’s Blue Origin’s mission. I’m super passionate about it.

Levy: Do you feel that it’s a bit disconnected to start a space-exploration company in this economically grim time?

Bezos: No. We employ a lot of aerospace engineers. They have families, their kids go to college. We buy a lot of materials. Somebody made those materials, right?

I don’t even understand that last question, but note the use of the e-word. I wish we could get people to think about space in terms other than science and exploration.

[Late morning update]

This is sort of related. Lileks isn’t impressed with the Kindle Fire.

Business, Economics, Political Commentary, Science And Society, Technology and Society

The Avastin Decision

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Did the FDA do the right thing?

The Wall Street Journal, and others, have denounced the FDA’s move as “a chillingly blunt assertion of regulatory power.” But my Manhattan Institute colleague Paul Howard is the guy who gets it right, in a blog post for Medical Progress Today:

If you think (as I do) that the FDA should be expanding the accelerated approval pathway and allow more drugs to get to market based on promising early studies. rather than waiting for large Phase III clinical trials that can take years to complete, you can argue that this outcome actually strengthens AA. Critics have charged that AA is sop to industry, and that companies never do the follow up studies to support AA. Avastin proves them wrong.

This is exactly the point. If you want the FDA to approve more innovative, new drugs based on promising but early clinical results, you have to give the FDA a way to revoke those approvals later on, should larger trials prove that those drugs aren’t as safe or effective as they first seemed. This is why the FDA should be congratulated for the way it has handled the Avastin breast cancer saga, and why I hope we will see the FDA handle more cases like this one, not less.

Yes, this is better than the way they’ve done it in the past, but this argument presumes that the FDA should have such regulatory power in the first place. It’s one thing to provide data on efficacy. It’s another to prevent people from making their own decisions about what drugs to use for which ailments.